Mohave Substance Treatment Education & Prevention Partnership (MSTEPP) is located in Mohave County, Arizona, and spans 13,461 miles, making it the fifth-largest county geographically in the United States. MSTEPP led the formation of an OFR team that includes all three communities in the county and served as a pilot site for the implementation of ODMAP in Arizona. The success of ODMAP in its community led to the expansion of ODMAP to 36 communities across the state. MSTEPP also trained and equipped two school districts with naloxone and worked with the Substance Abuse Coalition Leaders of Arizona to develop a school board policy template for districts desiring to bring naloxone into their facilities. MSTEPP also fostered successful partnerships with many local organizations—including the Kingman, Arizona, Chamber of Commerce, focused on educating local businesses about and equipping them with naloxone; the Chamber of Commerce now functions as a distribution point and training center for businesses that want to have naloxone within their establishments.