WestCare Tennessee, Inc., used its RROE project to provide services in Cocke and Jefferson Counties in Eastern Tennessee. Cocke County’s overdose rate in 2021 was nearly double the national rate, and Jefferson County’s opioid prescribing rate was more than double the national rate. WestCare Tennessee implemented seven different evidence-based prevention and education programs for youth and parents, provided job and community life skills training to individuals in both the Cocke County and Jefferson County Jails, and established ODMAP in both counties to identify high-risk drug traffic areas where education and prevention efforts should be focused.